Risk Factor: C
Class: Serums, toxoids, and vaccines/ Vaccines
Fetal Risk Summary
Tularemia vaccine is a live, attenuated bacteria vaccine (1,2). Tularemia is a serious infectious disease occurring primarily in laboratory personnel, rabbit handlers, and forest workers (1). The risk to the fetus from the vaccine is unknown. One report described vaccination in a woman early in the 1st trimester with transplacental passage of antibodies (2,3). No adverse effects were observed in the term infant or at 1-year follow-up. Because tularemia is a severe disease, preexposure prophylaxis of indicated persons should occur regardless of pregnancy (1).
Breast Feeding Summary
No data are available.
- Amstey MS. Vaccination in pregnancy. Clin Obstet Gynaecol 1983;10:1322.
- Albrecht RC, Cefalo RC, O’Brien WF. Tularemia immunization in early pregnancy. Am J Obstet Gynecol 1980;138:12267.
- Linder N, Ohel G. In utero vaccination. Clin Perinatol 1994;21:66374.