VACCINE, SMALLPOX
Drugs in Pregnancy and Lactation.
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Name: VACCINE, SMALLPOX
Class: Vaccine
Risk Factor: X
Fetal Risk Summary
Smallpox vaccine is a live, attenuated virus vaccine (1,2). Although smallpox infection had a high mortality rate, the disease has been largely eradicated from the world (1,3). Vaccination during pregnancy between 3 and 24 weeks has resulted in fetal death (2,3). A 1974 Reference reviewed the published reports of smallpox vaccination during pregnancy and found 20 cases of fetal vaccinia among more than 8,500 maternal vaccinations (4). Of the 21 exposed fetuses (1 set of twins), only 3 of the 10 liveborns survived. There was only weak evidence, however, that vaccination during the 1st trimester increased fetal wastage compared with that occurring later in gestation (4).
Although the incidence of fetal vaccinia with subsequent poor outcome resulting from maternal vaccination appears to be rare, most sources consider smallpox vaccine to be contraindicated during pregnancy (1,2 and 3,5).
Breast Feeding Summary
No data are available.
"Official medicines" is the best online drugstore.World’s leading meds delivered to your door – and you don’t even need a prescription! Only certified, first class drugs on offer! Buy more and spend less with our great discount system. |
References
- Amstey MS. Vaccination in pregnancy. Clin Obstet Gynaecol 1983;10:13–22.
- American Hospital Formulary Service. Drug Information 1997. Bethesda, MD: American Society of Health-System Pharmacists, 1997:2646–9.
- Hart RJC. Immunization. Clin Obstet Gynaecol 1981;8:421–30.
- Levine MM. Live-virus vaccines in pregnancy. Risks and recommendations. Lancet 1974;2:34–8.
- Linder N, Ohel G. In utero vaccination. Clin Perinatol 1994;21:663–74.
Q&A about Vaccine Smallpox
Here an interesting question.
How is a smallpox vaccine manufactured for the military when it is supposed to be wiped out?
I can't seem to think of any other diesase used other the cowpox..
How does the smallpox vaccine work. I heard something about B cells and Vaccina?!
If anyone has any websites with good scientific detail too I'd appreciate it!
Thanks.
how was the smallpox vaccine discovered
Cowpox is similar enough to smallpox to confer some immunity to smallpox. Yet cowpox isn't very dangerous to humans.
This lead to the idea of innoculating against the virus using cowpox.Which is what they initially did.
My daughter is doing a paper on smallpox and would like a picture of a person that has that scar. Neither my wife nor my scar still shows and we dont want to ask someone else. Please help!
I was Wondering if anyone knew where I could Get a Smallpox vaccine or even a doctor that can administer the vaccine?
They can also give a referral.
i am having trouble thinking of a way to start off my paper i have no clue!!! can someone help me
Look at the history of the vaccine. When did they first discover that dairymaids who had been exposed to cowpox (yeah, I said COWpox) didn't get smallpox? Who did the first vaccine (it was a live cowpox virus) and how long was it until he had convinced people to do vaccinations? When did it become a wide spread vaccination practice (sometime last century). What were the side effects? Why did they stop doing the vaccinations in the 70s?
Go into the disease, its effects, its long term effects on survivors, how many people it killed, the cycles it would show up in (every 20 or so years {figure out how many, the info is out there} it would break out big again and decimate chunks of the world). How do you tell it apart from chickenpox?
Why am I being so helpful? Cause I just finished a major lit review paper and am having fellow-feeling for anyone stuck with an assignment and no idea of how to start.
Smallpox is actually a very interesting disease. Check out the CDC website for basic info, and when you google it, make sure the sites you use are creditable. Also, google OWL at Purdue for writing tips.
Good luck!
Why is there a vaccine for smallpox, but not for HIV?
Websites, especially biochemical, would be great.
Thanks!
I received the smallpox vaccine in preparation for a deployment to the middle east. The area where the 3 pricks were applied is still a raised area. How long will this area stay like this? My test was negative but the scar is still there, it is really annoying.
I am thinking about going back into the armed forces, I have been out for a few years and I want to know if I will be forced to recieve either of these vaccines? I am willing to get the Smallpox, but I will not get the Anthrax.
