VACCINE, HEPATITIS B

Drugs in Pregnancy and Lactation.

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Name: VACCINE, HEPATITIS B
Class: Vaccine
Risk Factor:    CM

Fetal Risk Summary

Hepatitis B virus vaccine inactivated (recombinant) is a noninfectious surface antigen (HBsAg) vaccine (1,2). Animal reproduction studies have not been conducted with the vaccine.

No risks to the fetus from maternal vaccination have been reported (1,2). One source recommends that administration after the 1st trimester, because of a theoretical risk of teratogenicity, is preferred (3). The Centers for Disease Control and Prevention (CDC) states that there is no apparent risk of fetal adverse effects (based on unpublished CDC data) and that pregnancy is not a contraindication to vaccination in women (1). Pre- and postexposure prophylaxis is indicated in pregnant women at high risk of infection (2,4). (See also Immune Globulin, Hepatitis B).

Breast Feeding Summary

No data are available, but the vaccine is not contraindicated during lactation (1).

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References

  1. CDC. Hepatitis B virus: a comprehensive strategy for eliminating transmission in the United States through universal childhood vaccination. Recommendations of the Immunization Practices Advisory Committee (ACIP). MMWR 1991;40(No. RR-13):1–25.
  2. American College of Obstetricians and Gynecologists. Immunization during pregnancy. Technical Bulletin. No. 160, October 1991.
  3. Linder N, Ohel G. In utero vaccination. Clin Perinatol 1994;21:663–74.
  4. Faix RG. Maternal immunization to prevent fetal and neonatal infection. Clin Obstet Gynecol 1991;34:277–87.

Index

Q&A about Vaccine Hepatitis B

Amy S
Is it harmful to take the Hepatitis B vaccine twice?
I can't remember if I've had the Hepatitis B vaccine before, but I need it for a job. Should I go ahead and get it again?
emt_me91...
Nope.

It won't hurt you. I have had the Hep B vaccine 13 times. However, it was only because I didn't convert...my body failed to produce antibodies and I'm not immune to it. This is not common.

If you are offered it, go ahead and get it. Your employer should cover the cost.

EMT
rising_d...
Would a hepatitis B vaccine be necessary for a person with HBsAg positive and then recover from it later on?
Would a hepatitis B vaccine be necessary for a person with HBsAg positive once and in a period of time she went for another test and the test comes out negative?
AndreasD...
If the second test comes negative, the vaccine may be useful. But it is even not necessary, if you don't belong to a high risk group.
Kris
Do most hospitals and clinics require you to get a hepatitis B vaccine to be employed there?
I will soon be looking for work as a respiratory therapist in various hospitals and clinics, and I was wondering if any require the hepatitis B vaccine. I'd like to decline getting it and avoid it.
CJ
http://www.thinktwice.com/

Vaccines are dangerous.
Me
When you put the vaccine for Hepatitis B how long does it last you?
I had the shot when I was younger its been a couple of year. They just called me from the doctor to tell me that something came out either because I currently have it or because I had it when I was younger which is not possible because I have the Vaccine (unless it expired). I've been told that when you have the vaccine and you get tested it will show active and they will make retake the test is this true? This happened to me last year I got tested for Hepatitis C and something showed up and they made me get tested again and everything came back fine. Now, its happening with Hepatitis B. Thank you!
janeyfre...
They say it lasts anywhere from a few months to 6 years. It depends on your immune system which is particular to each individual.

Some vaccines don't take at all, because your body never produced antibodies.

If it's been since childhood and you absolutely need to get one, go ahead, but if you don't need it, don't get it.

In my opinion, the risks sometimes outweigh the supposed benefits.

If you have never had risky sex, been a drug user, etc. then you could have gotten some type of hepatitis in your blood stream from the vaccine which will never become a full blown illness.

Some people have HIV forever and it never turns into AIDS, they never die from it.

The immune system is a very complex thing, and it is unique to each individual.
LuvBNAMo...
Has your baby received the Hepatitis B vaccine and if so, did you research it first?
I wasn't prepared to make the decision of whether or not to have my child vaccinated with the Hepatitis B vaccine 16 hours after he was born. I was told it was routine and so agreed to it. After researching it online I've read many negative things about it and even found a doctor who said he does not give this vaccine in his office to infants because it just hasn't been out there long enough. I regret allowing all those chemicals into my son's body so early on. I'm aware of how Hepatitis B is contracted and my child would have to be bitten my another infected with the disease to get it, because he certainly won't be having sex or using IV drugs in the near future. I'm not against the vaccine per say but would like to wait at least until he is of school age to receive it. I personally think there are way too many chemicals being injected into infants before there immune systems have the chance to develop. My son was premature so his immune system is even more immature.
KS4E
I didn't research it first but decided to get the vaccine after a relative was diagnosed with Hep. C from a blood transfusion that wasn't properly screened. I figured that there was no telling what could happen in the near future and that it was better to be safe than sorry. As soon as our children are born, we put them at risk and it's best to do all we can to keep them safe. Even some things that are meant to keep them safe (like a blood transfusion to save his or her life) can go awry. It's so difficult to raise children but at least I know that I did all I could to give my child the best.
sweetnes...
tenderness and lump after hepatitis b vaccine?
I had to get my first hepatitis b vaccine yesterday before starting my new job. It stung a little when they were injecting the stuff in but all night long my arm hurt and today it's tender to the touch, hurts if I move my arm and there is a lump where they shot it in. Is this normal? I got a tetanus shot on my other arm and last time I got the tetanus shot I remember my arm being pretty sore, but this time it's way less tender than the HepB shot.
Megan M
yes, i've gotten them. and also give them all the time as i am a nurse. they can make your arm really sore. it will go away, and the lump will too.
PA grad student
What is the rate of failure for the Hepatitis B vaccine?
I have had the Hepatitis B Series of vaccinations twice - once in 1998 and again in 2006. Each time I was sure to go by the posted quidelines of when all 3 shots should be administered - however twice the blood work has came back that i was not immunte. Once in 2006 - hence the second series and again last week. I will be working in public health and will likely get a third series of vaccinations - but was curious if anyone knew why this may be happening.
Dee S
I had the same thing happen to me. The Doc explained to me that "some people just don't take to it". I am a smoker (cigarettes) and he said sometimes that is a factor - but not always. If you haven't been protected in the past - it's not likely that further vaccinations will be successful.

Good luck!
manish mishra
if somebody have taken first vaccine of hepatitis B,and make physical relation with Hepatitis B person?
IF somebody make relation with Hepatitis B person and that person allready taken first vaccine for that...and also used condom ,so what is the chance to get infection?
Dr.Ahmed
1st dose of vaccine is the main dose and the other successive 2 are stimulatory but they are important to synergies the response of ur immunity to Hep. B virus.

However Hep. B virus concentration in body fluids except blood is relatively low so it is most likely will not cause infection in the presence of vaccine and condom.
LittleMe...
What is an employers responsibility in reference to providing staff in a medical office Hepatitis B vaccine?
I work for a dentist who didn't flat out refuse to pay for the employees Hepatitis B vaccines/boosters, but he did make the comment that he expected us all to have this taken care of before mid November. When I responded that money was really tight right now before Christmas, especially with my husband out on medical leave for 10 weeks, and could we find a really cheap place, he responded " You know, you need this for your JOB. And if you don't have this job, you wouldn't be having much of a Christmas anyways, so I would think that this would be pretty important to take care of, wouldn't you?"

After checking with some others in the medical field, including other doctors, I was told that there is an OSHA law that required employers to provide this shot free of charge to any employee who is exposed to human blood, fluids, or waste. This would obviously include me and my co-workers.

Does anyone know about this law and could help me get the info?
Sophiesm...
I dont know about outside but i know in the military anyone who in the medical field was exposed to blood, fluids and waste had to get Hepvac series and tested for HIV every six months....I worked in surgery and you had to have this done... You would think it would be the same outside....Its for your safety and the safety of the patients....Call OSHA...
thugz4re...
Does the hepatitis b vaccine ever expire?
I got it about 8 years ago and need to know if i need to get it again since i'll be shadowing my dentist and it's required that i have a hepatitis b shot.
jasiek13...
The vaccination against hep B protects you till the end of your days. You don't need the booster/additional doses. PS. Do you remember the vaccination schedule? 3 doses or more? Or maybe the only one injection (in this case my answer will be much different)