Tridihexethyl
Risk Factor: C
Class: AUTONOMICS
/ Parasympatholytics (Anticholinergics)
Contents of this page:
Fetal Risk Summary
Breast Feeding Summary
References
Questions and Answers
Fetal Risk Summary
Tridihexethyl is an anticholinergic quaternary ammonium chloride. In a large prospective study, 2,323 patients were exposed to this class of drugs during the 1st trimester, 6 of whom took tridihexethyl (1). A possible association was found between the total group and minor malformations, but the significance of this is unknown. Independent confirmation is required (1).
Breast Feeding Summary
No data are available (see also Atropine).
References
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Heinonen OP, Slone D, Shapiro S. Birth Defects and Drugs in Pregnancy. Littleton, MA: Publishing Sciences Group, 1977:34653.
