Thiopropazate in pregnancy and breastfeeding

Thiopropazate]]>

Risk Factor: C
Class: Central nervous system drugs/ Tranquilizers

Contents of this page:
Fetal Risk Summary
Breast Feeding Summary
References

Fetal Risk Summary

Thiopropazate is a piperazine phenothiazine in the same group as prochlorperazine (see Prochlorperazine). Phenothiazines readily cross the placenta (1). No specific information on the use of thiopropazate in pregnancy has been located. Although occasional reports have attempted to link various phenothiazine compounds with congenital malformations, the bulk of the evidence indicates that these drugs are safe for the mother and fetus (see also Chlorpromazine).

Breast Feeding Summary

No data are available.

References

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  1. Moya F, Thorndike V. Passage of drugs across the placenta. Am J Obstet Gynecol 1962;84:177898.

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