QUINAPRIL

Drugs in Pregnancy and Lactation.

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Name: QUINAPRIL
Class: Antihypertensive
Risk Factor:    CM*

Fetal Risk Summary

Quinapril is an angiotensin-converting enzyme (ACE) inhibitor. No teratogenic effects were observed in reproduction studies in rats and rabbits with doses 180 and 1 times the maximum recommended human dose, respectively (1).

No reports of the use of this agent in human pregnancy have been located, but this class of drugs should be used with caution, if at all, during gestation. Use of ACE inhibitors limited to the 1st trimester does not appear to present a significant risk to the fetus, but fetal exposure after this time has been associated with teratogenicity and severe toxicity in the fetus and newborn, including death. See Captopril or Enalapril for a summary of fetal and neonatal effects from these agents.

[*Risk Factor DM if used in 2nd or 3rd trimesters.]

Breast Feeding Summary

No reports describing the use of quinapril during lactation have been located. Because other ACE inhibitors are excreted into breast milk, the passage of quinapril into milk should also be expected. The American Academy of Pediatrics considers both captopril and enalapril to be compatible with breast feeding (see Captopril and Enalapril).

Reference

  • Product information. Accupril. Parke-Davis, 2000.

    Index

    Q&A about Quinapril

    School Store Lady
    I'm on Quinapril and I have a horrible head cold. I used to take Dayquill. What do I take now?
    I usually take OTC stuff for colds/allergies but I think the stuff I'm on now isn't supposed to be taken with OTC stuff. What do I do to alleviate the sneezing, drippy nose, stuff head congestion?
    Mom_of_t...
    Take a hot bath, wrap yourself up in very heavy blankets (it will sweat your body out and release the toxins that are causing you to feel so badly). Drink hot herbal tea with lemon every hour or so. Avoid spicy food or cold drinks -anything that will aggravate it as sometimes colds can go to the throat too. Rest your head but sleep in an upright position so that you can rest easier. Get plenty of vitamin c and water. Honey also has some healing effects and can be good on warm toast. Soup is also perfect. But I don't recommend taking anything otc as nowadays they are having so many recalls (like the recent one on acetominiphin pain reliever pills). Just let it run its course and be sure to stay warm and keep your head and feet warm and dry. You'll feel better gradually but sleep, fuids, and rest are best.
    Ronan M
    Quinapril tablets?
    Can anyone tell me what happens if I stop taking quinapril tablets?
    huggz
    Tivar is quite right, and you will also be putting your kidneys at risk of damage and ultimate failure;