PYRANTEL PAMOATE
Drugs in Pregnancy and Lactation.
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Name: PYRANTEL PAMOATE
Class: Anthelmintic
Risk Factor: C
Fetal Risk Summary
No reports on the use of this drug in human pregnancy have been located. Shepard cited two studies in which no congenital defects or postnatal effects were observed in pregnant rats fed doses up to 3000 mg/kg or in pregnant rabbits given 1000 mg/kg (1,2).
Breast Feeding Summary
No data are available.
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References
- Owaki Y, Sakai T, Momiyama H. Teratological studies on pyrantel pamoate in rats. Oyo Yakuri 1971;5:41–50. As cited in Shepard TH. Catalog of Teratogenic Agents. 6th ed. Baltimore, MD: Johns Hopkins University Press, 1989:536.
- Owaki Y, Sakai T, Momiyama H. Teratological studies on pyrantel pamoate in rabbits. Oyo Yakuri 1971;5:33–39. As cited in Shepard TH. Catalog of Teratogenic Agents. 6th ed. Baltimore, MD: Johns Hopkins University Press, 1989:536.
Q&A about Pyrantel Pamoate
Adult monkeys to be given anthelmintic but I only have pyrantel pamoate. How often should I give the medication?
Pyrantel pamoate is a non-prescription medication. It is taken once a definite diagnosis of worms has been made by either seeing the worms or doing a transparent (cellophane) tape test. It may also be used if mebendazole (a prescription medication) is not effective.
Pyrantel pamoate kills adult worms. It does not kill worm eggs. Multiple doses several weeks apart are often used to treat or prevent parasite infestations. Elimination of parasites must also include sanitation and prevention measures to ensure the pet does not become reinfected.
Pyrantel should be administered in a single oral dose determined on the basis of body weight, e.g:Humans 11 mg/kg.
Use in animals over 2 weeks of age: Dose: 5 mg/kg (PO)
Toxicity: Cats: 100 mg/kg daily for 3 days produced no side effects, a single dose of 230.6 mg/kg produced vomiting and diarrhea in 2/92 cats.
Dogs: Acute LD50 dose is over 690 mg/kg, dogs given 20 mg/kg daily for 3 months had no problems, although dogs given 50 mg/kg for the same length of time did have signs of toxicity.
Pyrantel acts as a neuromuscular blocker so that the parasite relaxes its grip, effectively paralyzing the worm so that it loses its attachment. The worm is then passed with the feces into the cold, cruel world. Outside of the host protective body, the worm soon dies. Because the medication is absorbed poorly from the host’s intestine, the host is completely unaffected by the paralysis effect. It also helps that the host is substantially larger than the parasite, thus the small amounts of medication needed to remove parasites are not of concern to the mammal host.
Would either be suitable for feline treatment?
We just adopted a 10-week old puppy. She's received two treatments for both worms (pyrantel pamoate for hook and praziquantel for tape). The shelter said it could take up to four treatments for her to be in the clear. Based on your experience, how long does it take?
The puppy can also be started on Interceptor heartworm preventative now, even though he won't have his first heartworm check until he's 9 months old. Interceptor has medication in it to help keep intestional parasite in check.
Good Luck
I was at the vet today and didn't even think about the fact that I wasn't sure how to give this dewormer medicine I've got. And I would call the vet, but they're closed for another hour for lunch, so if I don't get an answer here within the hour I'll call, but just thought I'd check here first.
The medicine is pyrantel pamoate dewormer and it's in a syringe with no needle. I'm assuming I put it in her mouth but figured I should double check.
I received a kitten from someone who took in a stray pregnant cat and allowed her to give birth inside his home. The kitten is now 5 weeks of age. When should i get him his shots and deworm him.
Also, does anyone know of a place where you can buy pyrantel pamoate to deworm him?
6-8 weeks (Kittens can be dewormed at this age)
FVRCP vaccination No. I
(Feline viral rhinotracheitis, calici virus, panleukoenia, chlamydia)
Fecal examination
Blood test for Feline Leukemia virus (FelLV) and Feline Immunodeficiency virus (FIV)
12 weeks
FVRCP vaccination No. 2
FeLV vaccination No. I
Possible second fecal exam
16 Weeks
FeLV vaccination No. 2
Rabies vaccination
Pets should be vaccinated annually for most vaccines, after the initial booster series is administered to kittens. Some vaccines can be boostered every three (3) years. Remember that vaccines stimulate the immune system to produce antibodies to fight off viruses. Boosters must be given for the immune system to make long-term protection, antibodies that stay around for long periods of time.
Please note: If a pet has never received a vaccine before, and is over 16 weeks old, it will need one additional dose in 3 to 4 weeks before starting on the annual or triennial schedule.
An annual visit to your veterinarian provides an opportunity for a routine health check as well as any re-vaccinations that are necessary. If, for any reason, your pet misses a vaccination which has been advised by your veterinary practice, contact them for advice as soon as possible.
**Important note : Please do not deworm your young kitten with OTC. It is better to have the vet administer his first worming medicine and ask your vet to advice you on further worming medications.
Since everyone says dewormers sold at Petsmart can kill my kittens, can I buy something online?
Nearest vet is 2 hours away and my kittens get car sick... and they always overcharge me....
How about DRONTAL (for cats)... "The only broad-spectrum dewormer with the convenience of one dose administration for cats. Drontal contains praziquantel/pyrantel pamoate/febentel. Indicated for removal of tapeworms, hookworms, roundworms, and whipworms." 50 tabs $157
It says NO PRESCRIPTION REQUIRED, even though DRONTAL for dogs is require.
So is this medicine effective? If they only have tapeworms, would this medicine hurt them if they don't have the other worms listed?
And one of my kittens continues to have loose stools (not completely diarrhea) and a pot belly (signs of worms) but no worms were ever seen in his stool like the other on so would it hurt him if I gave him the medicine too?
Also should I get dewormers for my dogs too because they shared food and water with them?
I recently got an 8 wk old shepheard mix puppy from a local animal shelter. The shelter said she was healthy when I got her, but a few days ago she started coughing alot. The vet said she had an upper respitory congestion, along with something wrong with her stiches that she has from being spaid. He prescribed to her Guaifensn100/Dextromthrpn10mg, Clavamox, and Tobramycin Ophthalmic solution. Being on the meds for a couple of days she began to be better, but then i noticed some dried up things in her kennel, that looked like rice grains. I continued to watch her and the next morning her poop was crawling with worms. There about an inch long, moving all around, and white. The thing is though, she just had an intestinal parasite fecal exam and a pyrantel pamoate dewormer done six days ago on her initial vet visit. The vet said they don't have any appointments open today though, so i'm taking her in tommorow morning. Should I buy a dewormer on my own? Should i be worried?
You should take her to the vet and they will deworm her again. Deworming her yourself could be dangerous and is not recommended unless you have plenty of experience. Medicines to rid dogs of parasites and bugs are basically pesticides, so the improper use of them can serious harm and even kill your puppy.
We found our horse lying down in the arena. When I went in, she wouldn't get up without us putting a halter on her. She was breathing pretty hard; and it's hot out here. She also pooped while lying down which seemed weird. When she stood, we found she was extremely sweaty under her forelegs and between her back ones. None of our other three horses, also in said arena, are sweaty at all or showing signs of problems. We looked it up in the book and it said the sweat could be signs of some kind of insecticide poisoning. It also mentioned the name of a worming paste we recently gave her called Pyrantel Pamoate. We want to call the vet, but he's only available if it's an emergency. So do you think it is??? Should we call????????????
PS. She has pooped twice more and she is swatting her tail back and forth almost constantly. I don't think it's colllic though...
It's a HUGE emergency!
what's her temp? Did you check it? That will tell you if you are dealing with possible heat stroke.
If her temp is over 103 start hosing her down with cold water while you wait for the vet
So..go call!
***edit***
Thank goodness! Pooping laying down is not good..but he pooped! I'm so happy for you!
My girlfriend called me to let me know her boy was down. Not rolling, breathing fast and hard. What's up? Temp normal but he just doesn't want to get up..and he's sweaty. Minor colic. Why? He was witnessed cribbing all the day, nonstop while watching them bring some freshly cut hay. He was over excited (he has a bad grazing area so was just beside himself it seems when he seen the hay)
