PIPERAZINE
Drugs in Pregnancy and Lactation.
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Name: PIPERAZINE
Class: Anthelmintic
Risk Factor: B
Fetal Risk Summary
No published reports linking the use of piperazine with congenital defects have been located. A review of the treatment of threadworm infestation during pregnancy cited a personal communication involving two infants with congenital malformations who were exposed to piperazine (1). One of the infants had bilateral harelip, cleft palate, and anophthalmia, but exposure to piperazine had occurred at 12 and 14 weeks' gestation. The mother in the second case had taken the anthelmintic at 6 and 8 weeks' gestation and her infant had a defect of the right foot. Based on the scarcity of reports, the possibility of a causal relationship in the latter case is probably remote.
The Collaborative Perinatal Project monitored 50,282 mother-child pairs, 3 of which had 1st trimester exposure to piperazine. No evidence was found to suggest a relationship to malformations (2).
Breast Feeding Summary
Piperazine is excreted in breast milk (2), but specific data have not been located. According to one reviewer, the mother should take her dose of the drug immediately following feeding her infant, and then express and discard her milk during the next 8 hours (2).
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References
- Heinonen OP, Slone D, Shapiro S. Birth Defects and Drugs in Pregnancy. Littleton, MA: Publishing Sciences Group, 1977:299.
- Leach FN. Management of threadworm infestation during pregnancy. Arch Dis Child 1990;65:399–400.
Q&A about Piperazine
piperazine?
How come piperazine is a listed ingredient in 'legal highs' that are sold in some countries (my own included), yet none of its 'e-sensory' side effects are ever listed under its worming use?
How come piperazine is a listed ingredient in 'legal highs' that are sold in some countries (my own included), yet none of its 'e-sensory' side effects are ever listed under its worming use?
Guess the FDA has not tested it. Good question.
what is Piperazine Hydrochloride, and what are the main side effects?
I understand that this is in the formulae for 'herbal ecstasy', along with Kratom Extract, black pepper extract and Piperazine blend. are there any liekly side effects from this combination of drugs/ingrediants?
I understand that this is in the formulae for 'herbal ecstasy', along with Kratom Extract, black pepper extract and Piperazine blend. are there any liekly side effects from this combination of drugs/ingrediants?
This is the main ingredient in wormer for pets.
Exposure Routes: inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms: Irritation eyes, skin, respiratory system; skin burns, sensitization; asthma; gastrointestinal upset, headache, nausea, vomiting, incoordination, muscle weakness
Target Organs: Eyes, skin, respiratory system, central nervous system (NIOSH, 2003)
Melting Point: 635° F (NIOSH, 2003)
Molecular Weight: 159.1 (NIOSH, 2003)
TLV TWA: 5 mg/m3 (ACGIH, 2003)
Water Solubility: 41 % (NIOSH, 2003)
Exposure Routes: inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms: Irritation eyes, skin, respiratory system; skin burns, sensitization; asthma; gastrointestinal upset, headache, nausea, vomiting, incoordination, muscle weakness
Target Organs: Eyes, skin, respiratory system, central nervous system (NIOSH, 2003)
Melting Point: 635° F (NIOSH, 2003)
Molecular Weight: 159.1 (NIOSH, 2003)
TLV TWA: 5 mg/m3 (ACGIH, 2003)
Water Solubility: 41 % (NIOSH, 2003)
how bad is an overdose of liquid wormer piperazine citrate?
I dosed my approx. 10 lb cat with a 1 teaspoon dose of the wormer. He has vomited a few times, and had diarheal, he has also become lethargic. I believe that I overdosed him on accident, now how do I fix him?
I dosed my approx. 10 lb cat with a 1 teaspoon dose of the wormer. He has vomited a few times, and had diarheal, he has also become lethargic. I believe that I overdosed him on accident, now how do I fix him?
you cant fix him, he will have to metabolize it and if it doesnt kill him if can cause some neuralogical issues. I suggest you take the cat to the vet so they can administer some charcoal and get the some of that absorbed but if you let it get this bad then you really cant do anything but sit back and hope he comes out of it.
please read this page about Piperazine poisoning
http://www.peteducation.com/article.cfm?...
please read this page about Piperazine poisoning
http://www.peteducation.com/article.cfm?...
what is piperazine dihydrochloride?
i have a box of pills that contain piperazine dihydrochloride...what is that and what does it do?
i have a box of pills that contain piperazine dihydrochloride...what is that and what does it do?
piperazine dihydrochloride (pī′par·ə′zēn dī′hī·drə′klör′īd)
(organic chemistry) C4H10N2·2HCl White, water-soluble needles; used for insecticides and pharmaceuticals.
(organic chemistry) C4H10N2·2HCl White, water-soluble needles; used for insecticides and pharmaceuticals.
does hartz ultra guard rid worm paste for cats really work it says the main ingredient is piperazine is it saf
Do not use hartz products on your cats! They are linked to the deaths of several animals! Please see the following site and ask yourself if the low cost is really worth the risk to your pet, when a vet visit is so much safer?
http://www.hartzvictims.org/
http://www.hartzvictims.org/
does the wormer medication that contains piperazine also kill the tapeworm as well as the round worm in cats?
In my experience, there is no pill that does tapeworm and roundworm. Strongid does roundworm and Droncit does tapeworm. Never use over the counter flea meds or dewormer meds. They can be dangerous. Make sure you get all your meds from your vet.
How early in a kitten's life can you give them over the counter de-worming medication?
I bought the Hartz Ultra Guard Rid Worm Paste, it is 200 mg Piperazine. When is it safe to give this to a small kitten? Is it dangerous or health risk to give it sooner than 6 weeks of age, or less than 2 lbs.
I bought the Hartz Ultra Guard Rid Worm Paste, it is 200 mg Piperazine. When is it safe to give this to a small kitten? Is it dangerous or health risk to give it sooner than 6 weeks of age, or less than 2 lbs.
i think the general rule of thumb is always seek help from the vet and never try to treat any ailments by yourself because over the counter medications pretty much never work and might have some adverse side-effects...
what is HT--101 dioxo piperazine carbonyl chloride (EDPC) ,ahd what is it used for?
this ia a kind of chemical,maybe used in medicine making.
this ia a kind of chemical,maybe used in medicine making.
its a pharmaceutical raw aterials use for synthesizing organosilicon intermediates, such as the cephalosporin antibiotics: piperacillin, cefoperazone, etc.
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Are most dewormer's safe to use on cats?
My cat has worms I believe I found a small white worm around his anus. I have no idea how he got worms because him and all my other cats are inside animals. I have liquid wormer that can be used on dogs and cats and I was wondering if piperazine is safe. Thanks.
My cat has worms I believe I found a small white worm around his anus. I have no idea how he got worms because him and all my other cats are inside animals. I have liquid wormer that can be used on dogs and cats and I was wondering if piperazine is safe. Thanks.
Piperazine is the active ingredient used to treat common roundworms (ascariasis) and pinworms (enterobiasis; oxyuriasis) in cats, dogs and even humans. Read the label of your dewormer and give your kitties the correct dosage.
However, the worm you saw stiking on your cat's butt may be a tapeworm segment, which wi indicate that your cat has tapeworm. Cats and dogs get tapeworm from ingesting fleas. If the "worm" you saw looked like a grain of cooked rice, then it is tapeworm segment. That segment is full of eggs which gets released into the environment when the segment dries and bursts open. Flea larvae eat the eggs and pass them on to the cat or dog which eats the adult flea.
If it is tapeworm, then Piperazine will not work. You'll need Praziquantel. You can buy a bottle of Tapeworm Tabs at Petco or PetSmart and follow the directions for dosing very carefully. You'll need to weigh your cat. Also, if it is tapeworm, you'll need to treat your pets and their environment for fleas, otherwise, they may ingest an infected flea again and the tapeworm problem comes back.
However, the worm you saw stiking on your cat's butt may be a tapeworm segment, which wi indicate that your cat has tapeworm. Cats and dogs get tapeworm from ingesting fleas. If the "worm" you saw looked like a grain of cooked rice, then it is tapeworm segment. That segment is full of eggs which gets released into the environment when the segment dries and bursts open. Flea larvae eat the eggs and pass them on to the cat or dog which eats the adult flea.
If it is tapeworm, then Piperazine will not work. You'll need Praziquantel. You can buy a bottle of Tapeworm Tabs at Petco or PetSmart and follow the directions for dosing very carefully. You'll need to weigh your cat. Also, if it is tapeworm, you'll need to treat your pets and their environment for fleas, otherwise, they may ingest an infected flea again and the tapeworm problem comes back.
