Pentaerythritol Tetranitrate]]>

Risk Factor: C
Class: Cardiovascular drugs/ Vasodilators

Contents of this page:
Fetal Risk Summary
Breast Feeding Summary
References

Fetal Risk Summary

Pentaerythritol tetranitrate is a long-acting agent used for the prevention of angina pectoris. Because of the nature of its indication, experience in pregnancy is limited.

The Collaborative Perinatal Project recorded 3 1st trimester exposures to pentaerythritol tetranitrate plus 12 other patients exposed to other vasodilators (1). From this small sample, four malformed children were produced, a statistically significant incidence (p

Breast Feeding Summary

No data are available.

References

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  1. Heinonen OP, Slone D, Shapiro S. Birth Defects and Drugs in Pregnancy. Littleton, MA: Publishing Sciences Group, 1977.

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