Risk Factor: C
Class: Central nervous system drugs/ Antidepressants
Fetal Risk Summary
No reports describing the use of this monoamine oxidase inhibitor in human pregnancy have been located. No teratogenic effects were observed in the offspring of female rats administered this drug before and during gestation, and to the pups after weaning (1). However, decreased fertility and neurobehavioral changes were observed in the young rats (1).
Breast Feeding Summary
No data are available.
- Tuchmann-Duplessis H, Mercier-Parot L. Modifications du comportement sexual chez des descendants de rats traites par un inhibiteur des monoamine-oxydases. C R Acad Sci (Paris) 1963;256:22357. As cited in Shepard TH. Catalog of Teratogenic Agents. 6th ed. Baltimore, MD: Johns Hopkins University Press, 1989:447.