METHANTHELINE

Drugs in Pregnancy and Lactation.

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Name: METHANTHELINE
Class: Parasympatholytic (Anticholinergic)
Risk Factor:    C

Fetal Risk Summary

Methantheline is an anticholinergic quaternary ammonium bromide. In a large prospective study, 2,323 patients were exposed to this class of drugs during the 1st trimester, 2 of whom took methantheline (1). A possible association was found between the total group and minor malformations.

Breast Feeding Summary

No data are available (see also Atropine).

Reference

  • Heinonen OP, Slone D, Shapiro S. Birth Defects and Drugs in Pregnancy. Littleton, MA: Publishing Sciences Group, 1977:346–53.

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