IOPANOIC ACID
Drugs in Pregnancy and Lactation.
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Name: IOPANOIC ACID
Class: Diagnostic
Risk Factor: D
Fetal Risk Summary
Iopanoic acid contains a high concentration of organically bound iodine. See Diatrizoate for possible effects on the fetus and newborn.
Breast Feeding Summary
Iopanoic acid is excreted in breast milk. Cholecystography was performed in 11 lactating patients with iopanoic acid (1). The mean amount of iodine administered to 5 patients was 2.77 g (range 1.98–3.96 g) and the mean amount excreted in breast milk during the next 19–29 hours was 20.8 mg (0.08%) (range 6.72–29.9 mg). The nursing infants showed no reaction to the contrast media. The American Academy of Pediatrics considers iopanoic acid to be compatible with breast feeding (2).
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References
- Holmdahl KH. Cholecystography during lactation. Acta Radiol 1956;45:305–7.
- Committee on Drugs, American Academy of Pediatrics. The transfer of drugs and other chemicals into human milk. Pediatrics 1994;93:137–50.
