FLUNITRAZEPAM

Drugs in Pregnancy and Lactation.

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Name: FLUNITRAZEPAM
Class: Hypnotic
Risk Factor:    D

Fetal Risk Summary

Flunitrazepam is a benzodiazepine (see also Diazepam). No reports linking the use of flunitrazepam with congenital defects have been located, but other drugs in this group have been suspected of causing fetal malformations (see also Diazepam or Chlordiazepoxide). In contrast to other benzodiazepines, flunitrazepam crosses the placenta slowly (1,2). About 12 hours after a 1-mg oral dose, cord:maternal blood ratios in early and late pregnancy were about 0.5 and 0.22, respectively. Amniotic fluid:maternal serum ratios were in the 0.02–0.07 range in both cases. Accumulation in the fetus may occur after repeated doses (1).

Breast Feeding Summary

Flunitrazepam is excreted into breast milk. Following a single 2-mg oral dose in five patients, mean milk:plasma ratios at 11, 15, 27, and 39 hours were 0.61, 0.68, 0.9, and 0.75, respectively (1,2). The effects of these levels on the nursing infant are unknown but they are probably insignificant.

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References

  1. Kanto J, Aaltonen L, Kangas L, Erkkola R, Pitkanen Y. Placental transfer and breast milk levels of flunitrazepam. Curr Ther Res 1979;26:539–45.
  2. Kanto JH. Use of benzodiazepines during pregnancy, labour and lactation, with special Reference to pharmacokinetic considerations. Drugs 1982;23:354–80.

Index

Q&A about Flunitrazepam

jlx02000
Is Hynor realy a brand name for Zopiclone or Flunitrazepam?
I have doing some research on Hynor which i have recently received from Egypt. It says that it is A brand of Zopiclone but i feel it is different. I usually take Zopiclone or Zopiclon. My research suggests (BNF reports) That it actually Flunitrazepam which is Rohypnol which is far from what i want

Is this true? Dr's and Pharmacists and patients please.

No well wishing suggestions just the answer please. Maybe Dr Frank might want to check this out again!
Ian
Flunitrazepam is the generic name for Rohypnol. As far as I know Zopiclone is the generic name for Imovane and Zimovane or Lunestain the USA.

There are many other Trade names for Zopiclone

i.e Hypnor - Egypt it must be a typing error in the original information you have received from Egypt

AN expert Patient !
Bjunior
Is 30mg of flunitrazepam enough to put you out?
Orinoco
Yes in most cases. In the case of someone who is hyped up on drugs, angry, or having a large body mass you might need more.
audaciou...
If I was slipped Flunitrazepam or a "roofey" in my drink what should I do to prevent it from affecting me? Ex.
A girl was slipped a roofey and she found out before it took full affect, what should she do? If she goes to sleep is that ok if she is somewhere safe?
kim
If this ever happens again, take the person to the hospital immediately. You can never be sure what exactly was in the drug that was slipped to her and she could be allergic to something in the pill or liquid. Even though she was brought to a safe place to sleep it off, she could have vomited in her sleep and asperated, or gotten some of the vomit in her lungs. That can cause death in and of itself, to say nothing of the fact that people have drowned on their vomit before. The drug could have also caused her to go into seizures. If the worse had happened and she had died, the people that brought her to the safe house and anyone there could have been charged in her death even though you didn't give her the drug/

Whoever did this needs to be prosecuted. They could have killed her and in the very least, they certainly wanted to rape her. And that is what it is when someone is drugged or gotten too drunk to be able to say yes or no.

You were a good friend to try to help. Now you can be an even better friend if this ever happens again. Be safe and remember if your hand is not on your drink at all times, preferably with your hand over the top, DON'T DRINK IT!
Kevin P
what is flunitrazepam,gamma-hydroxybutyrate?
C Anderson
Imagine benzodiazepine on steroids.

As a "date rape drug", probably nothing you should be fooling around with. If you're in the U.S., mere possession can land you in the clink right quick -- it's not FDA approved here, so there's no legitimate use. Most of it in the U.S. comes up illegally from Mexico (like so many things that ought not).

The trade name is Rohypnol (courtesy of Hoffmann-La Roche).