DOXAZOSIN

Drugs in Pregnancy and Lactation.

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Name: DOXAZOSIN
Class: Sympatholytic (Antiadrenergic)
Risk Factor:    CM

Fetal Risk Summary

Doxazosin is a peripherally acting a1-adrenergic blocking agent used in the treatment of hypertension. No adverse fetal effects were observed when pregnant rats and rabbits were given oral doses 4 and 10 times the human serum levels achieved with a 12 mg/day therapeutic dose (HD), respectively (1). However, reduced fetal survival occurred in rabbits dosed at 20 times the HD and delayed postnatal development was observed in rat pups whose mothers were given doses 8 times the HD during the perinatal and postnatal periods (1). Doxazosin crosses the placenta in rats (1).

No reports describing the use of doxazosin in human pregnancy have been located.

Breast Feeding Summary

Doxazosin is concentrated in the milk of lactating rats given a single oral dose of 1 mg/kg with peak levels about 20 times those achieved in the maternal serum (1). No reports describing the use of doxazosin during human lactation have been located. However, the presence and possible accumulation in human milk should be anticipated based on the animal study.

Reference

  • Product information. Cardura. Pfizer, 2000.

    Index

    Q&A about Doxazosin

    darkling
    Did they send me home with useless medication?
    so I got a kidney stone with real bad pain and they sent me home with doxazosin mesylate..metoclopramide and ibuprofen..from what i can look up thats bld pressure pills, anti nausea pills and some useless painkillers.

    I had to go back to hospital and they gave me morphine and that barely helped with the pain. Am I wrong or did they send me home with a whole bunch of stupid pills in the first place.
    melisker
    Sounds like they did.....

    If you are passing a kidney stone (I answered your other Q.) you need major pain killers. (Painkillers are not an automatic addiction-they do serve a purpose, just make sure you use them to your Dr.'s directions)

    I would DEMAND something stronger, at least vicodin or percocet.

    Best of luck again!
    roger k
    im on blood pressure tabs..diovan160mg and doxazosin 4mg.. ive lost my sex drive. and cant get an solid erect?
    got told its the tabs im 50 and had a high sex drive
    checkthi...
    My husband had a heart attack last June, he is only 40. His doctor put him on blood pressure pills and he had the same problem as you because of it. He could get an erection but it went away. Once his blood pressure stabilized, his body got used to having lower blood pressure, his erections are almost 100% back to normal. This was a big problem for him, having a very high sex drive and all. Before his body got used to a lower bp his doctor gave him Viagra. We used to laugh about it before his heart attack, but not anymore. If taking a pill could restore his sex life, then he was willing to take the thing. He figured who would know anyway. It wasn't his fault that he had this problem and nothing he could do about it. After he got over the shame our sex life returned to normal. Just something for you to think about and maybe discuss with your doctor.