Digoxin

 Risk Factor: CM
 Class: CARDIOVASCULAR DRUGS / Cardiac Drugs

Contents of this page:

Fetal Risk Summary
Breast Feeding Summary
References
Questions and Answers

Fetal Risk Summary


See Digitalis.

Breast Feeding Summary


See Digitalis.

Questions and Answers

What would you expect if DIGOXIN after 4 years has NOT been effective?, Your 80 year old client has been on digoxin 0.25mg. p.o. once a day for four years now. What behaviours would you expect to see if his medication has NOT been effective? What things in his stimulus pool might be contributing to his increasing heart failure?

Are you sure its not working? Maybe if he/she wasn't on it they would have had complete heart failure several years ago. Just something to consider.

Is digitek the same medication as digoxin?, I am a 21 year old heart patient who has been taking digoxin for 2 years. I recently found out about the digitek recall and want to know if I can get any compensation from the manufacture.

You must have damages. If you received the double strength tablets, you would have known and you would have damages. I have been a pharmacist for 30 years and this is the worst F up I have seen. Just be glad you have no damages(I hope).

What effect would the acidty of orange juice have on digoxin/digitoxin over a few days?, I am a mystery writer trying to figure out if digoxin or digitoxin would be altered in a highly acidic environment like orange juice over the course of several days. I am wokring on a murder premise wherein the killer spikes orange juice with digoxin and I am wondering how long it would be potent.

Hi mcgo,
Check at http://www.webmd.com/. Good Luck: Blueladybug

I would like to ask about taking Nitroglycrin and digoxin intake in an empty stomach?, For the people they suffer a heart failure could them to take the Nitroglycrin and digoxin as medicine for the disease while there stomachs are empty? please let me know as soon as you my good friends have the right answer.
Thank you so much for you nice sharing and help.

It is not necessary to take either medication on an empty stomach. Nor is it required for them to be taken with food.

A prescription is received in the community pharmacy for 12mcg of digoxin /lanoxin for a 6 month infant with a?, congenital heart problem to be taken once daily. The stock supply of digoxin is 0.125 mg/ 5ml. How much medication will be required for a 30 day supply of the medication ? Explain how you obtain the answer. The rest of the question is above.

12mcg x 30 days = 360mcg of digoxin for the 30 days
360mcg = 0.36mg

0.36mg / 0.125mg/5mL = 14.4mL

Therefore 14.4mL of the stock supply of digoxin is required for the month supply of the prescription

What would happen if a patient was given a double dose of digoxin for two weeks.?, I am a pharmacy intern and my pharmacy manager asked me this question and I can't find what would happen. Please include where you got your sources. Thanks!

The correct answer is "It depends." It depends on the following things: Digoxin level, renal function, comorbidities, other medications they are taking (i.e. amiodarone, quinidine, verapamil), electrolytes (esp. hypokalemia and hypomagnesemia) etc... If the digoxin level comes back toxic (usually > 2.5), the patient may experience signs / symptoms of dig toxicity. Early symptoms include nausea & vomiting, loss of appetite, diarrhea, headache, and weakness. Later symptoms may include visual disturbances (the classic halo effect that you always here about), confusion, seizures, cardiac dysrhythmias, hallucinations, and even death. Every patient is different and will respond differently. If the patient is in dig tox, you give Digibind. Hope this helps.

What is the toxicity of digoxin?, Can it really bring the heartbeat to a dead stop? Is this true, literally? Is it just one extra dose or is it like a dozen or more overdoses which can do this? How narrow is the margin?

Digoxin's narrow therapeutic range (0.8 to 2 ng/ml) makes toxicity quite common: It's estimated to be present in 5% to 20% of all hospitalized patients on digoxin. Testing serum drug levels about 8 hours after each drug administration helps detect toxicity. Log and report digoxin levels greater than 2 ng/ml and a heart rate below 60 bpm; these are key indicators of digoxin toxicity, though many patients who are on digoxin routinely have heart rates below 60 bpm.

Renal insufficiency, drug interaction, hypercalcemia, hypokalemia, hypomagnesemia, hypothyroidism, and advanced age all increase the risk of digoxin toxicity. (See Raising the Risks for common drugs that can cause problems.) Gastrointestinal symptoms of toxicity include anorexia, nausea, and vomiting. Neurologic symptoms include headaches, malaise, fatigue, neuralgic pain, dementia, seeing yellow or green halos around objects, and seizures. Cardiac signs include functional rhythms, heart blocks, ventricular rhythms, acute tachycardia, and bradycardia.

Where would Digoxin go on the Schedules of Controlled Substances?,

Digoxin is a prescription-only medication, but not a controlled substance.

Usually, the schedule of a drug really only matters if it is a controlled substance (schedule 1-5). These are ranked more or less by how likely they are to be abused or cause addiction.

Sometimes drugs like digoxin (prescription but not controlled) are classified as schedule 6, but usually, when something is said to be "scheduled", it means schedules 1-5.

Hope that helps!

how much of Ouabain gives the same inotropic effect of Digoxin?, Ouabain is the cardiac glycoside that is widely used in research while Digoxin is the most clinically used as an inotropic agent.The question is how much Ouabain is equivalent to Digoxin ? please guide me to the source of information.

I am a pharmacist and I am not aware of the existence of equivalency data. You would be safer to use Digoxin exclusively, it's dosage and monitoring parameters are well known.

What is the maximum dose of oral Digoxin for a 4- month old baby!?, The baby is 4 months old and weighing 7 Kg. Could the maximum dose be 250 microgram per day per oral??

The maximum daily dose would be 84mcg/day. This is based on a dose of 12mcg/kg/day. Consult a Physician for the appropriate dose.



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