DEXTROTHYROXINE

Drugs in Pregnancy and Lactation.

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Name: DEXTROTHYROXINE
Class: Antilipemic
Risk Factor:    C

Fetal Risk Summary

Dextrothyroxine is the dextro-isomer of levothyroxine (see also Levothyroxine). Although formerly used to treat hypothyroidism, the drug is now used exclusively for the therapy of hyperlipidemia. In a study of placental passage of dextrothyroxine, approximately 9% of a radiolabeled dose given 2–8 hours before delivery was found in the cord blood (1). Except for this one report, no mention of its use in human pregnancy has been located.

Breast Feeding Summary

No data are available.

Reference

  • Kearns JE, Hutson W. Tagged isomers and analogues of thyroxine (their transmission across the human placenta and other studies). J Nucl Med 1963;4:453–61.

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