Anisindione
Risk Factor: D
Class: Hematological agents
/ Anticoagulants
Contents of this page:
Fetal Risk Summary
The indandione derivative, anisindione, is an oral anticoagulant. It is structurally related to phenindione, an anticoagulant not available in the United States.
In an investigation of the effects of occlusive thromboaortopathy (Takayasu's disease) on pregnancy, 4 of 27 women were maintained on anisindione throughout five pregnancies (1). No neonatal complications or anomalies were observed in the five infants. (See Coumarin Derivatives.)
Breast Feeding Summary
See Coumarin Derivatives.
References
-
Ishikawa K, Matsuura S. Occlusive thromboaortopathy (Takayasu's disease) and pregnancy: clinical course and management of 33 pregnancies and deliveries. Am J Cardiol 1982;50:12931300.
